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Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
No clinical assertions recorded for an overview.
View full clinical evidence and sources ↓Clinical evidence
Dose regimens0
No dose regimens recorded for this species selection.
Adverse effects200
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Vomiting12,831 reports
- Seizure NOS6,910 reports
- Lack of efficacy (bacteria) - Borrelia6,734 reports
- Lack of efficacy (endoparasite) - heartworm6,095 reports
- Diarrhoea5,215 reports
- Lack of efficacy (endoparasite) - hookworm4,343 reports
- Lack of efficacy (ectoparasite) - tick NOS4,174 reports
- Lethargy (see also Central nervous system depression in 'Neurological')3,557 reports
- Lack of efficacy (endoparasite) - roundworm NOS3,314 reports
- Lack of efficacy (ectoparasite) - flea2,719 reports
- Tremor2,382 reports
- Lack of efficacy (endoparasite) - tapeworm2,326 reports
Cat
- Application site hair loss2,294 reports
- Application site alopecia707 reports
- Application site scab686 reports
- Lack of efficacy (ectoparasite) - flea685 reports
- Vomiting682 reports
- Lethargy (see also Central nervous system depression in 'Neurological')678 reports
- Application site reddening489 reports
- Application site irritation343 reports
- Seizure NOS337 reports
- Lethargy (see also Central nervous system depression in Neurological)326 reports
- Anorexia303 reports
- Not eating291 reports
Literature references5
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Efficacy of Revolution(®) Plus (selamectin plus sarolaner) for the prevention of transmission of Borrelia burgdorferi from infected Ixodes scapularis to cats.
Study summary not available in the imported record. Open the original citation to review the study.
- Efficacy of a spot-on combination product containing selamectin and sarolaner (Stronghold(®) Plus) in the treatment of naturally occurring Notoedres cati infestations in cats.
Study summary not available in the imported record. Open the original citation to review the study.
- Sarolaner/selamectin spot-on: An effective treatment of generalized demodicosis due to Demodex cati in a cat.
Study summary not available in the imported record. Open the original citation to review the study.
- Efficacy of Revolution®Plus in cats for the prevention of Dipylidium caninum transmission by infected Ctenocephalides felis.
Study summary not available in the imported record. Open the original citation to review the study.
- Efficacy of Revolution® Plus (selamectin plus sarolaner) against Amblyomma americanum (lone star ticks) in cats.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration.
Available products
Products listed in the Health Canada Drug Product Database for this active ingredient. A listing does not establish that a product is authorized for the clinical uses described on this page.