Favorites and recent references stay on this device. No patient data is stored.
Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
Choose one species to view its source overview. All-species evidence remains available below.
View full clinical evidence and sources ↓Clinical evidence
Pending clinical review (PROPOSED)Rule-based (RULE_BASED)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens1
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
Choose one species above to view its dose calculator.
Adverse effects201
Hypermagnesemia: CNS depression, weakness, bradycardia, hypotension, ↑QT, respiratory depression, neuromuscular block → arrest
Other speciesNot applicable (NOT_APPLICABLE)1 source record · View provenance
- Other species · Plumb's Veterinary Drug Handbook, 7th ed., p. 1062–1064 (NaHCO₃), p. 749–750 (magnesium), p. 504–505 (IVFE), p. 647–648 insulin monograph (dextrose hypoglycemia guidance) — Side Effects / Adverse Effects table · Not applicable · Not applicable (NOT_APPLICABLE) · Pending clinical review (PROPOSED) · Rule-based
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Diarrhoea26 reports
- Vomiting26 reports
- Other abnormal test result NOS18 reports
- Elevated alanine aminotransferase (ALT)13 reports
- Lack of efficacy - NOS11 reports
- Lethargy (see also Central nervous system depression in 'Neurological')11 reports
- Weight loss11 reports
- Anorexia10 reports
- Lethargy (see also Central nervous system depression in Neurological)10 reports
- Neutrophilia10 reports
- Not eating10 reports
- Elevated serum alkaline phosphatase (ALP)9 reports
Cat
- Vomiting10 reports
- Other abnormal test result NOS6 reports
- Diarrhoea5 reports
- Elevated blood urea nitrogen (BUN)5 reports
- Elevated creatinine5 reports
- Anorexia4 reports
- Death by euthanasia4 reports
- Lethargy (see also Central nervous system depression in 'Neurological')4 reports
- Urinary bladder disorder NOS4 reports
- Abnormal ultrasound finding3 reports
- Dehydration3 reports
- Hypoglycaemia3 reports
Literature references15
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Magnesium oxide nanoparticles: A novel shield against CCl₄-induced hepatic damage via caspase-3 and TNF-α in rats.
Study summary not available in the imported record. Open the original citation to review the study.
- Bridging in vitro buoyancy to clinical performance: A PBPK-driven analysis of once-daily Bepotastine gastro-retentive tablet in beagles and humans.
Study summary not available in the imported record. Open the original citation to review the study.
- A randomized controlled trial of intravenous magnesium sulfate shows no analgesic or anti-inflammatory benefit in dogs undergoing thoracolumbar disk herniation surgery.
Study summary not available in the imported record. Open the original citation to review the study.
- Evaluation of bioactive scaffold magnesium-containing hydroxyapatite from biomass resources for supporting osteogenesis, angiogenesis, andin vivobone regeneration.
Study summary not available in the imported record. Open the original citation to review the study.
- Concentrations of essential and non-essential elements in eastern North Pacific killer whales (Orcinus orca).
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration; Plumb DC. Plumb's Veterinary Drug Handbook. 7th ed. PharmaVet Inc; 2011.