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Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
No clinical assertions recorded for an overview.
View full clinical evidence and sources ↓Clinical evidence
Dose regimens0
No dose regimens recorded for this species selection.
Adverse effects101
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Vomiting14 reports
- Death9 reports
- Depression7 reports
- Ataxia6 reports
- Anorexia4 reports
- Recumbency4 reports
- Trembling4 reports
- Convulsion3 reports
- Diarrhoea3 reports
- Dyspnoea3 reports
- Neurological signs NOS3 reports
- Shaking3 reports
Cat
- Vomiting10 reports
- Ataxia8 reports
- Twitching7 reports
- Death6 reports
- Accidental exposure5 reports
- Convulsion5 reports
- Hypersalivation4 reports
- No sign4 reports
- Depression3 reports
- Diarrhoea3 reports
- Mydriasis3 reports
- Weakness3 reports
Literature references19
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Optimization and Antibacterial Evaluation of Novel 3-(5-Fluoropyridine-3-yl)-2-oxazolidinone Derivatives Containing a Pyrimidine Substituted Piperazine.
Study summary not available in the imported record. Open the original citation to review the study.
- Comparative evaluation of a novel piperazine-chalcone hybrid and calcium hydroxide formulations against root canal pathogens.
Study summary not available in the imported record. Open the original citation to review the study.
- Dysregulation of human ClpP using small molecules with piperazine-based scaffold for diffuse intrinsic pontine glioma therapy validated by patient-derived tumor organoids.
Study summary not available in the imported record. Open the original citation to review the study.
- Frozen media preserves blastocyst development and quality in cattle embryos produced in vitro: a six-month evaluation.
Study summary not available in the imported record. Open the original citation to review the study.
- Machine Learning Reveals Amine Type in Polymer Micelles Determines mRNA Binding, In Vitro, and In Vivo Performance for Lung-Selective Delivery.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration.
Available products
Products listed in the Health Canada Drug Product Database for this active ingredient. A listing does not establish that a product is authorized for the clinical uses described on this page.