Favorites and recent references stay on this device. No patient data is stored.
Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
Dog · Applies to the overview and full clinical evidence below.
Indications 0
No indications recorded for this species.
Sourced dose regimens 1
0.3–1 mg/kg, q12h, PO
Pending clinical review (PROPOSED)Not applicable (NOT_APPLICABLE)Source: Table 1 (p.630), row: Memantine, DOG column
View source context
Pending clinical review (PROPOSED) Not applicable (NOT_APPLICABLE)
Not applicable · Manual (MANUAL)
Original excerpt: 0.3–1 mg/kg PO q12h
Contraindications 0
No contraindications recorded for this species.
Precautions 0
No precautions recorded for this species.
Monitoring 0
No monitoring recorded for this species.
Clinical evidence
Pending clinical review (PROPOSED)Manual (MANUAL)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens1
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
Dose calculation
Species: Dog. Results use the source regimens shown below.
- Review the source route shown below.
- Enter patient weight and its unit.
- For volume, optionally enter a matching label concentration.
Source route: Oral (PO)
- 0.3–1 mg/kgSource range: both endpoints are multiplied; no dose within the range is selected.Source regimen: 0.3–1 mg/kg, q12h, PO
Enter the patient’s weight above to multiply this source dose (or both range endpoints) by weight.
- Source formulation
- Not specified in this source
- Dose basis
- Not specified in this source
Adverse effects0
No adverse effects or event reports recorded for this species selection.
Literature references20
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Multi-Target Neuroprotective Compound Exhibits EAAT2-Modulating and Alzheimer's Pathology-Attenuating Effects in In Vitro and In Vivo Models.
Study summary not available in the imported record. Open the original citation to review the study.
- Neuroprotective effects of curcumin, memantine, and caffeic acid in a Rat model of cerebral ischemia-reperfusion injury.
Study summary not available in the imported record. Open the original citation to review the study.
- MeMAGEN: A Phase IIa/IIb open-label trial of memantine testing safety and tolerability in sickle cell patients.
Study summary not available in the imported record. Open the original citation to review the study.
- Memantine, an NMDA Receptor Antagonist, Attenuates Doxorubicin-Induced Cardiac Oxidative Stress and Inflammation in Mouse 4T1 Breast Cancer Model.
Study summary not available in the imported record. Open the original citation to review the study.
- Empagliflozin and memantine combination ameliorates cognitive impairment in scopolamine + heavy metal mixture-induced Alzheimer's disease in rats: role of AMPK/mTOR, BDNF, BACE-1, neuroinflammation, and oxidative stress.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; Perrin C, Seksel K, Landsberg GM. Appendix: Drug Dosage Chart. Vet Clin Small Anim 2014;44:629-632.