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Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
No clinical assertions recorded for an overview.
View full clinical evidence and sources ↓Clinical evidence
Dose regimens0
No dose regimens recorded for this species selection.
Adverse effects200
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Vomiting32 reports
- Death by euthanasia22 reports
- Lethargy (see also Central nervous system depression in 'Neurological')20 reports
- Elevated alanine aminotransferase (ALT)19 reports
- Not eating19 reports
- Death16 reports
- Other abnormal test result NOS16 reports
- Pain NOS16 reports
- Seizure NOS16 reports
- Elevated blood urea nitrogen (BUN)14 reports
- Anorexia13 reports
- Diarrhoea13 reports
Cat
- Lethargy (see also Central nervous system depression in 'Neurological')17 reports
- Behavioural disorder NOS16 reports
- Death15 reports
- Vomiting15 reports
- Anorexia13 reports
- Fever13 reports
- Lethargy (see also Central nervous system depression in Neurological)11 reports
- Death by euthanasia10 reports
- Weight loss10 reports
- Ataxia9 reports
- Elevated creatinine9 reports
- Other abnormal test result NOS9 reports
Literature references20
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Effects of Megasphaera elsdinii SC8-1 and Cutibacterium acnes SC8-2W supplementation on in vitro ruminal fermentation, methane emission, and their genomic attributes.
Study summary not available in the imported record. Open the original citation to review the study.
- Intravenous Bolus Fluid Therapy Versus No Fluid Therapy Prior to Pericardiocentesis in Dogs: A Randomized Controlled Trial in 30 Dogs.
Study summary not available in the imported record. Open the original citation to review the study.
- Lactate represses MHC-I antigen presentation via H4K5 lactylation-PRC2 in small cell lung cancer subtype A.
Study summary not available in the imported record. Open the original citation to review the study.
- Effects of an Iso-Osmotic Chloride-Free Solution With High Strong Ion Difference vs. Ringer's Lactate on Non-Lactate Metabolic Acidosis in Dogs.
Study summary not available in the imported record. Open the original citation to review the study.
- D-sodium lactate promotes the activation of NF-κB signaling pathway induced by lipopolysaccharide via histone lactylation in bovine mammary epithelial cells.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration.
Available products
Products listed in the Health Canada Drug Product Database for this active ingredient. A listing does not establish that a product is authorized for the clinical uses described on this page.