Favorites and recent references stay on this device. No patient data is stored.
Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
Choose one species to view its source overview. All-species evidence remains available below.
View full clinical evidence and sources ↓Clinical evidence
Pending clinical review (PROPOSED)Rule-based (RULE_BASED)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens2
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
Choose one species above to view its dose calculator.
Adverse effects200
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Emesis38 reports
- Lethargy (see also Central nervous system depression in 'Neurological')38 reports
- Vomiting35 reports
- Death19 reports
- Seizure NOS17 reports
- Diarrhoea16 reports
- Other abnormal test result NOS16 reports
- Anorexia15 reports
- Behavioural disorder NOS11 reports
- Cough10 reports
- Decreased appetite10 reports
- Lack of efficacy - NOS10 reports
Cat
- Vomiting10 reports
- Pruritus9 reports
- Other abnormal test result NOS8 reports
- Weight loss8 reports
- Not eating7 reports
- Sneezing7 reports
- Anaemia NOS6 reports
- Dehydration6 reports
- Lethargy (see also Central nervous system depression in 'Neurological')6 reports
- Decreased appetite5 reports
- Skin scab5 reports
- Ataxia4 reports
Literature references18
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Efficacy of dimetinden and hydroxyzine/chlorpheniramine in atopic dogs: a randomised, controlled, double-blinded trial.
Study summary not available in the imported record. Open the original citation to review the study.
- Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite.
Study summary not available in the imported record. Open the original citation to review the study.
- Interaction of Central Glutamatergic and Histaminergic Systems on Food Intake Regulation in Layer Chickens.
Study summary not available in the imported record. Open the original citation to review the study.
- Bioavailability of the Common Cold Medicines in Jellies for Oral Administration.
Study summary not available in the imported record. Open the original citation to review the study.
- Aedes (Stegomyia) aegypti mosquito bite hypersensitivity in a dog: a case report.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration; Plumb DC. Plumb's Veterinary Drug Handbook. 7th ed. PharmaVet Inc; 2011.