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Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
Choose one species to view its source overview. All-species evidence remains available below.
View full clinical evidence and sources ↓Clinical evidence
Pending clinical review (PROPOSED)Manual (MANUAL)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens2
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
Choose one species above to view its dose calculator.
Adverse effects7
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Administration error NOS1 reports
- Anorexia1 reports
- Elevated aspartate aminotransferase (AST)1 reports
- Vomiting1 reports
Cat
- Decreased heart rate1 reports
- Low blood pressure1 reports
- Twitching1 reports
Contraindications2
Hepatic dysfunction
DogCatNot applicable (NOT_APPLICABLE)2 source records · View provenance
- Dog · Table 1 (p.630), row: Naltrexone, Contraindications column · Not applicable · Not applicable (NOT_APPLICABLE) · Pending clinical review (PROPOSED) · Manual
- Cat · Table 1 (p.630), row: Naltrexone, Contraindications column · Not applicable · Not applicable (NOT_APPLICABLE) · Pending clinical review (PROPOSED) · Manual
Literature references14
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Case Series of Veterinary Cancer Patients Treated with Oral Low-Dose Naltrexone.
Study summary not available in the imported record. Open the original citation to review the study.
- Cardiovascular effects of a selective 5-HT4 agonist and an alpha-2 adrenoceptor antagonist in etorphine immobilised sheep (Ovis aries) - a randomised, prospective, and controlled trial.
Study summary not available in the imported record. Open the original citation to review the study.
- A systematic review and meta-analysis of the efficacy and safety of pharmacological treatments for obesity in adults.
Study summary not available in the imported record. Open the original citation to review the study.
- Development of the European Association for the Study of Obesity (EASO) Grade-Based Framework on the Pharmacological Treatment of Obesity: Design and Methodological Aspects.
Study summary not available in the imported record. Open the original citation to review the study.
- Butorphanol-azaperone-medetomidine and ketamine-butorphanol-azaperone-medetomidine chemical immobilization in habituated subadult female giraffe (Giraffa camelopardalis).
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration; Perrin C, Seksel K, Landsberg GM. Appendix: Drug Dosage Chart. Vet Clin Small Anim 2014;44:629-632.