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One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
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Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
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View full clinical evidence and sources ↓Clinical evidence
Pending clinical review (PROPOSED)Rule-based (RULE_BASED)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens1
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
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Adverse effects51
Hypoglycemia, vomiting, icterus (rare hepatic)
Other speciesNot applicable (NOT_APPLICABLE)1 source record · View provenance
- Other species · Plumb's Veterinary Drug Handbook, 7th ed., p. 573–574 (glipizide), p. 180–181 (calcitriol), p. 770–772 (megestrol) — Side Effects / Adverse Effects table · Not applicable · Not applicable (NOT_APPLICABLE) · Pending clinical review (PROPOSED) · Rule-based
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Drug dose administration interval too short1 reports
- INEFFECTIVE, GLYCEMIC CONTROL1 reports
- Overdose1 reports
Cat
- Ketosis5 reports
- Lethargy (see also Central nervous system depression in Neurological)4 reports
- Decreased appetite3 reports
- Vomiting3 reports
- Anxiety2 reports
- Behavioural disorder NOS2 reports
- Death2 reports
- Death by euthanasia2 reports
- Diabetic ketoacidosis2 reports
- Elevated alanine aminotransferase (ALT)2 reports
- Elevated globulins2 reports
- Hyperglycaemia2 reports
Interactions1
β-blockers mask hypoglycemia; NSAIDs potentiate (human)
Other speciesNot applicable (NOT_APPLICABLE)1 source record · View provenance
- Other species · Plumb's Veterinary Drug Handbook, 7th ed., p. 573–574 (glipizide), p. 180–181 (calcitriol), p. 770–772 (megestrol) — Drug Interactions table · Not applicable · Not applicable (NOT_APPLICABLE) · Pending clinical review (PROPOSED) · Rule-based
Literature references20
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Efficacy and Safety of Non-Insulin Antidiabetic Drugs in Cats: A Systematic Review.
Study summary not available in the imported record. Open the original citation to review the study.
- Pharmacokinetics Study of Herb-Drug Interaction of Berberine and Glipizide in Beagle Dogs Using UPLC-MS/MS.
Study summary not available in the imported record. Open the original citation to review the study.
- A model of type 2 diabetes in the guinea pig using sequential diet-induced glucose intolerance and streptozotocin treatment.
Study summary not available in the imported record. Open the original citation to review the study.
- TREATMENT OF DIABETES MELLITUS IN A GOLDEN LION TAMARIN (LEONTOPITHECUS ROSALIA) WITH THE GLUCAGON-LIKE PEPTIDE-1 MIMETIC EXENATIDE.
Study summary not available in the imported record. Open the original citation to review the study.
- [Development of glipizide push-pull osmotic pump controlled release tablets by using expert system and artificial neural network].
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration; Plumb DC. Plumb's Veterinary Drug Handbook. 7th ed. PharmaVet Inc; 2011.