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Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
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View full clinical evidence and sources ↓Clinical evidence
Pending clinical review (PROPOSED)Rule-based (RULE_BASED)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Dose regimens2
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
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Adverse effects163
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Emesis230 reports
- Vomiting172 reports
- Lethargy (see also Central nervous system depression in 'Neurological')130 reports
- Diarrhoea88 reports
- Other abnormal test result NOS78 reports
- Lack of efficacy - NOS77 reports
- Elevated serum alkaline phosphatase (SAP)45 reports
- Behavioural disorder NOS44 reports
- Elevated alanine aminotransferase (ALT)44 reports
- Seizure NOS43 reports
- Anorexia41 reports
- Decreased appetite40 reports
Cat
- Skin scab4 reports
- Death3 reports
- Inappetence3 reports
- Lethargy (see also Central nervous system depression in 'Neurological')3 reports
- Other abnormal test result NOS3 reports
- Biting -aggression (see also Skin and appendages disorders)2 reports
- Deafness NOS2 reports
- Ear infection NOS2 reports
- Excessive licking and/or grooming2 reports
- Hiding2 reports
- Itching2 reports
- Neoplasia NOS2 reports
Literature references16
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- Formulation and assessment of hydroxyzine HCL solid lipid nanoparticles by dual emulsification technique for transdermal delivery.
Study summary not available in the imported record. Open the original citation to review the study.
- Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites.
Study summary not available in the imported record. Open the original citation to review the study.
- Lack of preventing effect of systemically and topically administered histamine H(1) or H(4) receptor antagonists in a dog model of acute atopic dermatitis.
Study summary not available in the imported record. Open the original citation to review the study.
- Hydroxyzine and cetirizine pharmacokinetics and pharmacodynamics after oral and intravenous administration of hydroxyzine to healthy dogs.
Study summary not available in the imported record. Open the original citation to review the study.
- Rush allergen specific immunotherapy protocol in feline atopic dermatitis: a pilot study of four cats.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration; Plumb DC. Plumb's Veterinary Drug Handbook. 7th ed. PharmaVet Inc; 2011.