Robenacoxib

What is this medication for?

• Post-surgical/acute pain (US: max 3 days; EU: up to 6 days)
• Acute pain/inflammation (musculoskeletal, post-op); chronic OA (outside US)

How is it given?

Give exactly as your veterinarian prescribed — never change the dose or stop on your own unless your veterinarian has told you to.

• Wash hands after handling tablets; pregnant women near term advised to wear gloves (manufacturer instruction).

What if I miss a dose?

• Give it as soon as you remember — unless it is almost time for the next dose (then skip the missed one; never double up).
• Call your clinic if you miss more than one dose in a row.

Side effects — what should I watch for?

Effects listed as common in this handout

• stomach/intestinal (vomiting, soft feces, diarrhea) (Most common, usually mild/self-limiting)
• Blood in feces (Reported in some patients)

Worth a phone call to your veterinarian

• ↑ Liver enzyme activity (With long-term oral use (not always associated with pathology))

⚠️ Contact your veterinarian or an emergency clinic IMMEDIATELY if you notice

• Trouble breathing, collapse, seizures, severe vomiting or diarrhea, facial swelling, or pale gums

Before starting (or refilling), tell your veterinarian if your pet:

• has or has had: stomach/intestinal ulcers; hypersensitivity; hepatic disease (dogs)
• has or has had: Cardiac/renal impairment, dehydration, hypovolemia, low blood pressure; feline hepatic dysfunction; avoid with corticosteroids/other NSAIDs — observe ≥24h treatment-free period when switching

• is pregnant, nursing, or used for breeding
• is taking any other medications, supplements, or flea/tick products, including:
  • ACE inhibitors, diuretics
  • Aspirin, corticosteroids, other NSAIDs
  • Fluconazole
  • Highly protein-bound drugs
  • Methotrexate

Storage and handling

Protect from heat and moisture. Injectable: refrigerate (2–8°C).

Good to know

• Feed timing matters more than for most NSAIDs in cats — give without food (or only a small partial meal) to maximize absorption.
• Manufacturer explicitly prohibits mixing with other veterinary medicinal products (no compatibility data).
• Wash hands after handling tablets; pregnant women near term advised to wear gloves (manufacturer instruction).