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Choose the species
One selection filters the source overview, clinical facts, reports and dose calculator. Literature references are not species-filtered.
Choose one species for its overview and dose calculator, or all species to browse the full evidence.
Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
No clinical assertions recorded for an overview.
View full clinical evidence and sources ↓Clinical evidence
Dose regimens0
No dose regimens recorded for this species selection.
Adverse effects200
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Vomiting78 reports
- INEFFECTIVE, ANTIINFLAMMATORY71 reports
- Lack of efficacy - NOS65 reports
- Anorexia51 reports
- Elevated serum alkaline phosphatase (SAP)49 reports
- Death41 reports
- Lethargy (see also Central nervous system depression in 'Neurological')39 reports
- Elevated alanine aminotransferase (ALT)36 reports
- Polydipsia35 reports
- Depression34 reports
- Diarrhoea33 reports
- Other abnormal test result NOS33 reports
Cat
- Vomiting210 reports
- Anorexia205 reports
- Lethargy (see also Central nervous system depression in 'Neurological')178 reports
- Death173 reports
- Weight loss147 reports
- Death by euthanasia126 reports
- Hyperglycaemia125 reports
- Lack of efficacy - NOS125 reports
- Depression93 reports
- Other abnormal test result NOS93 reports
- Ataxia90 reports
- Abnormal radiograph finding85 reports
Literature references19
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- A longitudinal study of fractures in 1488 Thoroughbred racehorses receiving intrasynovial medication: 2006-2011.
Study summary not available in the imported record. Open the original citation to review the study.
- Use of ultrasound-guided percutaneous perineural corticosteroid injections for refractory cervical pain secondary to vertebral venous system abnormality in a dog.
Study summary not available in the imported record. Open the original citation to review the study.
- Hepatoprotective effects of mitoquinol mesylate in dogs with methylprednisolone acetate-induced steroid hepatopathy: A randomized crossover study.
Study summary not available in the imported record. Open the original citation to review the study.
- Intra-articular methylprednisolone acetate does not induce hyperinsulinemia or hyperglycemia in metabolically normal horses.
Study summary not available in the imported record. Open the original citation to review the study.
- Meta-Analysis and Mechanism-Based Modeling of Synovial and Plasma Pharmacokinetics and Adrenal Suppression Following Intra-Articular Injection of Methylprednisolone Acetate in Horses.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration.
Available products
Products listed in the Health Canada Drug Product Database for this active ingredient. A listing does not establish that a product is authorized for the clinical uses described on this page.