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Source overview
Recorded excerpts for one species. Each dose remains a separate source entry; no regimen is selected.
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Pending clinical review (PROPOSED)Rule-based (RULE_BASED)— applies to the facts and dose entries in this species selection; individual source records retain their own status.
Indications5
Staphylococcus aureus For intramammary use to reduce the frequency of existing infection and to prevent new infections within dry cows. INDICACIONES: Staphylococcus aureus Uso intramamario para reducir la frecuencia de la infección existente y prevenir nuevas infecciones poren vacas secas.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34067-9 (INDICATIONS & USAGE SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Pasteurella multocida Erysipelothrix rhusiopathiae Streptococcus equi Norocillin is indicated for treatment of bacterial pneumonia (shipping fever) caused byin cattle and sheep, erysipelas caused byin swine, and strangles caused byin horses.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34067-9 (INDICATIONS & USAGE SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Staphylococcus aureus and Streptococcus agalactiae. ALBADRY PLUS Suspension is indicated for the treatment, in dry cows only, of subclinical mastitis caused by susceptible strains of
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34067-9 (INDICATIONS & USAGE SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Pasteurella multocida Erysipelothrix rhusiopathiae Streptococcus equi PenOne Pro™ is indicated for treatment of bacterial pneumonia (shipping fever) caused byin cattle and sheep, erysipelas caused byin swine, and strangles caused byin horses.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34067-9 (INDICATIONS & USAGE SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Pasteurella multocida Erysipelothrix rhusiopathiae Streptococcus equi Bactracillin G is indicated for treatment of bacterial pneumonia (shipping fever) caused byin cattle and sheep, erysipelas caused byin swine, and strangles caused byin horses.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34067-9 (INDICATIONS & USAGE SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Dose regimens6
This calculator performs arithmetic only on the sourced dosing field shown for each result — it does not verify the field's accuracy, does not select which field to use for a patient, and does not replace a veterinarian's order. Not for clinical use. Confirm every result against the primary source before dispensing.
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Adverse effects164
These are counts of spontaneously reported events, not proven adverse effects, causal relationships, or incidence rates.
Bars compare report counts within each species; they do not show incidence.
More reportsFewer reportsDog
- Injection site abscess39 reports
- Injection site swelling28 reports
- Death22 reports
- Injection site necrosis12 reports
- Vomiting11 reports
- Convulsion10 reports
- Injection site pain10 reports
- Anaphylaxis9 reports
- Injection site lump8 reports
- Anorexia7 reports
- Fever7 reports
- Injection site inflammation7 reports
Cat
- Death11 reports
- Anaphylaxis8 reports
- Dyspnoea7 reports
- Anorexia5 reports
- Hypersalivation5 reports
- Vomiting5 reports
- Cardiac arrest4 reports
- Convulsion4 reports
- Respiratory distress4 reports
- Vocalisation4 reports
- Cyanosis3 reports
- Hypothermia3 reports
Contraindications1
It is your responsibility to inform your client of the warnings stated above so as to avoid adulteration of meat or milk and possible prosecution under Federal law. ATENCIÓN MÉDICO: Es su responsabilidad informar al cliente las advertencias establecidas anteriormente con el fin de evitar la adulteración de la carne o la leche, y una posible acusación según la ley federal.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34066-1 (Boxed Warning section) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Precautions8
For udder instillation upon drying off only. Not to be used within six (6) weeks of freshening. Not for use in lactating cows. Milk taken from animals within 96 hours (8 milkings) after calving must not be used for food. Animals infused with this product must not be slaughtered for food within 60 days from time of infusion nor within 96 hours after calving. ADVERTENCIAS: Únicamente para inst i lación al momento del secado. No utilizar dentro de las seis (6) semanas del período de producción de leche. No utilizar en vacas en período de lactancia. La leche ordeñada de los animales dentro de las 96 horas (8 ordeñes) después de la parición no se debe utilizar para alimentos. Los animales infundidos con este product no deben utilizarse como alimento dentro de los 60 días desde el momento de la infusión ni dentro de las 96 horas después de la parición.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34071-1 (WARNINGS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Do not use in horses intended for human consumption. Not for use in humans. Keep out of reach of children.
Species not recordedOn-label (ON_LABEL)United States3 source records · View provenance
- Species not recorded · SPL section 34071-1 (WARNINGS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
- Species not recorded · SPL section 34071-1 (WARNINGS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
- Species not recorded · SPL section 34071-1 (WARNINGS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Intramuscular injection in cattle, sheep, and swine may result in a local tissue reaction which persists beyond the withdrawal period of 14 days (cattle), 9 days (sheep), or 7 days (swine). This may result in trim loss of edible tissue at slaughter. Allergic or anaphylactic reactions, sometimes fatal, have been known to occur in animals hypersensitive to penicillin and procaine. Such reactions can occur unpredictably with varying intensity. Animals administered penicillin G procaine should be kept under close observation for at least one half hour. Should allergic or anaphylactic reactions occur, discontinue use of the product and call a veterinarian. If respiratory distress is severe, immediate injection of epinephrine or antihistamine following manufacturer's recommendations may be necessary. As with all antibiotic preparations, use of this drug may result in overgrowth of nonsusceptible organisms, including fungi. A lack of response by the treated animal, or the development of new signs or symptoms suggest that an overgrowth of nonsusceptible organisms has occurred. In such instances, consult your veterinarian. It is advisable to avoid giving penicillin in conjunction with bacteriostatic drugs such as tetracyclines. To report a suspected adverse reaction call 1-866-591-5777.
Species not recordedOn-label (ON_LABEL)United States3 source records · View provenance
- Species not recorded · SPL section 42232-9 (PRECAUTIONS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
- Species not recorded · SPL section 42232-9 (PRECAUTIONS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
- Species not recorded · SPL section 42232-9 (PRECAUTIONS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Administration of this product in any manner other than shown under DOSAGE may result in drug residues.
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 42232-9 (PRECAUTIONS SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Pharmacokinetics1
Infusion of antibiotics at the start of the drying off period has the following advantages: (1) it is active against existing infections; (2) it is prophylactic against new infections, during the time when cattle are likely to become infected [1]; (3) the antibiotic remains in the udder for a sufficiently long period to accomplish the intended objective and is not diluted with milk, as is the case in lactation therapy; (4) the danger of drug residues in the milk is reduced. Antibiotic control is to be considered an adjunct to good herd hygiene management and milking management. Detailed field studies in England and the United States have demonstrated that a program consisting of treatment, at the time of drying off, with a highly effective antibiotic preparation in a slow-release base, and routine dipping of teats after each milking with an effective disinfectant, markedly reduces the incidence of all udder infections at calving [2,3,4]. It has recently been recommended that a disinfectant teat dip be used on unmilked cows, or at least be used for 10 days before parturition [5], to reduce the bacterial challenge to the depleted levels of antibiotic in the teat as freshening is approached [6]. When the herd infection level has been reduced, or when herds are not heavily infected initially, it may be desirable to be selective in treating dry quarters [7]. ACCIÓN: La infusión de antibióticos al comienzo del período de secado tiene las siguientes ventajas: (1) es activa contra las infecciones existentes; (2) es profiláctica contra las nuevas infecciones durante el período en el que el ganado es propenso a contraer infecciones [1]; (3) el antibiótico permanence en la ubre por un período lo suficientemente largo como para lograr el objetivo y no se diluye con la leche, como pasa con la terapia en período de lactancia; (4) se reduce el peligro de que queden residuos del medicamento en la leche. El control con antibióticos debe considerarse un auxiliar de la buena gestión de higiene del Ganado y la gestión del ordeñe. Estudios de campo detallados realizados en Inglaterra y Estados Unidos han demostrado que un programa constituido por un tratamiento al momento del secado, con una preparación de antibióticos de liberación lenta altamente efectiva, y el sellado frecuente de los pezones con un desinfectante eficaz después de cada ordeñe, reducen considerablemente la incidencia de todas las infecciones de ubre en la parición [2, 3, 4]. Recientemente, se ha recomendado usar un sellador desinfectante de pezones en vacas no ordeñadas, o al menos usarlo 10 días antes del parto [5] para reducir el riesgo bacteriano a los niveles más bajos de antibiótico en el pezón cuando se acerca el período de producción de leche [6]. Cuando se haya reducido el nivel de infección del ganado, o en caso de que el ganado no esté muy infectado, es conveniente ser selectivo en el tratamiento de cuartos secos [7].
Species not recordedOn-label (ON_LABEL)United States1 source record · View provenance
- Species not recorded · SPL section 34090-1 (CLINICAL PHARMACOLOGY SECTION) · United States · On-label (ON_LABEL) · Pending clinical review (PROPOSED) · Rule-based
Literature references15
References are linked to this drug. Species applicability is not recorded here, so the species filter does not narrow this list. Imported dates do not retain their original precision; confirm dates in the original citation.
- High incidence of complications following intraoral extractions and treatment of periapical infections in the management of domestic rabbit (Oryctolagus cuniculus) dental disease (51 cases).
Study summary not available in the imported record. Open the original citation to review the study.
- Clinical Outcome of Transcervical Infusion of a Combination of Procaine Penicillin and Gentamicin in Late-term Pregnant Mares.
Study summary not available in the imported record. Open the original citation to review the study.
- An atypical Bacillus anthracis infection in a bull-A potential occupational health hazard.
Study summary not available in the imported record. Open the original citation to review the study.
- Evaluation of plasma concentration after intravenous and intramuscular penicillin administration over 24 hr in healthy adult horses.
Study summary not available in the imported record. Open the original citation to review the study.
- Microbial shifts in the swine nasal microbiota in response to parenteral antimicrobial administration.
Study summary not available in the imported record. Open the original citation to review the study.
Sources: DailyMed, U.S. National Library of Medicine; PubMed, National Library of Medicine; openFDA, U.S. Food and Drug Administration.
Available products
Products listed in the Health Canada Drug Product Database for this active ingredient. A listing does not establish that a product is authorized for the clinical uses described on this page.