Non-core vaccine decision-making

WSAVA guideline

Key findings

• Definitions: non-core = highly recommended only for at-risk animals (geography/lifestyle); "not recommended" = insufficient evidence anywhere (VGG 2024, Introduction).
• Leptospira is the boundary case: core where endemic + serogroups known + suitable vaccines exist; 2 doses 2–4 weeks apart then annual; restart 2 doses if ≥18 months lapsed (VGG 2024, Introduction; FAQs).
• Bordetella mucosal: single dose, annual, 13-month DOI; must never be injected parenterally; parenteral products need 2 doses 2–4 weeks apart (VGG 2024, Table 1).
• Borrelia (Lyme) and CIV: high-risk dogs only — Borrelia annually just before tick season (tick control is the mainstay; ACVIM consensus no agreement on routine use); CIV USA-licensed only, co-housed dogs, reduces severity not infection (VGG 2024, Table 1).
• Leishmania (A2, LiESP, recombinant Q): all annual, supplementary to ectoparasite control; vaccinated dogs can still transmit L. infantum; CHV-1 subunit is special-use for pregnant bitches (2-dose protocol in table) (VGG 2024, Table 1).
• Cats: FeLV non-core outside prevalent areas (risk-based); FIV (Japan/AU/NZ only) confounds antibody diagnostics, field efficacy 56%; C. felis and IN Bordetella only for sustained-risk/multi-cat settings (VGG 2024, Table 2).

Drugs named in WSAVA’s own guideline text

As printed in WSAVA’s document, not this app’s own extracted data — see “Related drugs in this reference” below for that.

• (Dog)

  Lapse ≥18 mo → restart

• (Dog)

  Pair with Bordetella mucosally

• (Dog)

  Never inject parenterally

• (Dog)

  Not IN/orally

• (Dog)

  Tick control mainstay

• (Dog)

  USA only; co-housed

• (Dog)

  Does not block transmission

• (Dog (pregnant bitches))

  Protects newborns

• (Cat)

  Test FeLV-negative first

• (Cat)

  Confounds serology

• (Cat)

  Multi-cat, confirmed disease

• (Cat)

  Large colonies

Recommendations

• Select non-core vaccines only after assessing lifestyle, geography, local prevalence

  Non-core (guiding principle)

• Leptospira for all dogs in endemic regions with known serogroups

  Core (regional) / Non-core elsewhere

• Bordetella ± CPiV mucosal vaccine for dogs at CIRDC risk

  Non-core for at-risk

• Borrelia (tick control), CIV (US co-housed), Leishmania and CHV-1 (pregnant bitches) only per documented risk

  Non-core (restricted)

• FeLV risk-based outside core-rule areas; FIV/C. felis for sustained-risk cats

  Non-core

• Do not use CCoV, Giardia, M. canis or FIP vaccines

  Not recommended

• Annual boosters for most non-core products

  Non-core interval rule

Related drugs in this reference (0)

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